Closed-loop anterior-insula high-gamma readout steers value-based decisions

• Nature Communications reports that closed-loop readout of anterior insula high-gamma activity can steer value-based decisions.¹
• The study used intracranial electrophysiology (iEEG/ECoG) to read anterior insula signals in real time.¹
• High-gamma activity in the anterior insula served as the neural readout for the closed-loop system.¹
• Closed-loop feedback based on that readout causally biased participants’ value-based choices.¹
• The approach demonstrates a decode-and-steer pipeline for closed-loop BCI and neuromodulation.^{1 1}

Footnotes

1. https://www.nature.com/articles/s41467-026-75265-5 ↩ ↩² ↩³ ↩⁴ ↩⁵ ↩⁶