Neural Noise

Ceribell

4 min read

  • Ceribell point-of-care EEG was named to Time Magazine’s Best Inventions of 2025.1
  • The recognition supports point-of-care EEG’s role in acute and clinical workflows and reflects mainstream validation.1
  • Commercial and clinical relevance for rapid EEG deployment; tier-1 source and existing product.1 1

Overview

Ceribell is a Sunnyvale, CA-based medical technology company commercializing a rapid-deployment, AI-powered point-of-care EEG platform for acute care.2 Founded in 2014 as Brain Stethoscope, Inc. by Stanford neurologist Josef Parvizi, Stanford composer/computer-scientist Chris Chafe, and CEO Xingjuan (Jane) Chao (PhD, Cornell biophysics; ex-McKinsey, Novartis, Genentech), the company evolved from a brainwave sonification art project into a clinical-grade EEG headband + AI seizure-detection system now installed in ~647 U.S. hospitals.34 It went public on Nasdaq (CBLL) in October 2024 at $17/share, closing the first day +47%.56

Timeline

YearMilestone
2014Founded as Brain Stethoscope, Inc. by Jane Chao, Josef Parvizi (Stanford), and Chris Chafe (Stanford); concept evolved from a brainwave-to-music sonification project into a clinical EEG company.4
2015 (Oct)Jane Chao takes the CEO role full-time.4
2018Commercial launch of the Ceribell System (rapid-deployment EEG headband + pocket recorder); closes ~$35M Series B co-led by The Rise Fund.78
2021 (Apr)$53M Series C co-led by Longitude Capital and The Rise Fund; RA Capital, Redmile, Red Tree, GE Ventures, LivaNova, UCB participate.8
2022 (Sep)$50M Series C extension led by Ally Bridge Group, bringing Series C total to ~$103M.7
2023 (Oct)FDA 510(k) clearance for the Clarity algorithm (status epilepticus detection) and CMS New Technology Add-on Payment (NTAP) coverage granted in the same window.9
2024 (Oct 10)IPO on Nasdaq (CBLL) priced at $17 (top of range), upsized to $180.3M (~$207M with overallotment); stock closes day one at ~$25 (+47%).56
2025 (Apr)FDA clearance of the Clarity algorithm for pediatric patients ages 1+ — first and only FDA-cleared AI for electrographic seizure detection in children at the time.10
2025 (Nov 24)FDA 510(k) clearance for Clarity in neonates and preterm infants — largest neonatal validation dataset (>700 patients).1112
2025 (Dec)FDA 510(k) clearance for first-of-its-kind EEG-based delirium monitoring (validated in 225 critical care patients).1314
2025Ceribell point-of-care EEG named to Time Magazine Best Inventions of 2025; FedRAMP High authorization enables VA deployment.111
2026 (Jan 5)FDA Breakthrough Device Designation for LVO (large vessel occlusion) stroke detection and monitoring; CBLL stock +8% on the news.1516
2026 (Feb)FY2025 results: $89.1M revenue (+36% YoY), 88% gross margin, $159M cash; ~3% penetration of an estimated ~6,000-hospital ICU/ED market.1117

Gardner updates

  • Ceribell received FDA clearance for a seizure-detection algorithm in neonates, expanding its EEG-based clinical neurophysiology portfolio in critical care. 18

  • Ceribell received FDA 510(k) clearance for a first-of-its-kind EEG-based delirium monitoring solution. 13

  • CeriBell reported Q4 revenue growth of 34% and projected revenue growth of 25%–29% for FY’26 (Nasdaq-sourced financials), signaling commercial traction for EEG/rapid response neurotech. 19

  • A March 2026 MSN/Google News item on Ceribell, Inc. (CBLL) states the company reported a Q4 loss while Q4 revenue beat prior revenue estimates (additional financial detail not in the excerpt). 20

  • FY2025 revenue was $89.1 million (36% YoY growth) with 88% gross margins; the company held $159 million in cash post-IPO and is installed in ~647 of an estimated ~6,000 U.S. hospitals with ICU/ED capability, representing only ~3% penetration of the seizure market.11

  • Platform expansion milestones: FDA 510(k) clearance for the Clarity algorithm in neonates and preterm infants (November 2025, largest neonatal validation dataset with >700 patients), clearance for delirium monitoring (December 2025, validated in 225 critical care patients), and FDA Breakthrough Device Designation for LVO stroke detection (January 2026).11

  • The Clarity algorithm achieves 95% sensitivity and 97% specificity for suspected status epilepticus at ≥90% seizure burden threshold; 99.9% NPV for ruling out seizure; validated across 135+ publications.21

  • The SAFER-EEG prospective multi-center trial showed early Ceribell use was associated with a 4.1-day shorter median ICU stay and 18% more patients with better neurological outcomes vs. conventional EEG.21

  • Revenue model is ~75% disposable headbands and ~25% subscription (the latter at ~97% gross margin); ClarityPro was the first critical care monitoring device to secure both FDA Breakthrough Designation and CMS New Technology Add-on Payment (NTAP) reimbursement at up to $913.90 per eligible Medicare patient.22

  • Total addressable market expanded to ~$3.5 billion with delirium and pediatric indications added; pediatric/neonate launch planned Q2 2026 targeting ~280 children’s hospitals; VA sales enabled by FedRAMP clearance in 2025.11

Footnotes

  1. https://news.google.com/rss/articles/CBMijgFBVV95cUxPRXEzT2FNZHhNR3k3N1FTWS1wX3ZSOHlBRHR1eVVMQTNhUG1uSEZJbTlfV3JyaFBvQ1Q4SVFzNjZHR2MzVkRjZ3dsYjdXRnVOYzlrdXdaYXVzWi1qWUFDRk91V0JTWnU5T3pwVFBULW1weEdNeEVsRm54b2NZZzVSZlRXZmQ3TmxXbzZTUFBH?oc=5 ↩ ↩2 ↩3 ↩4 ↩5

  2. https://ceribell.com/about-us/leadership-team/ ↩

  3. https://canvasbusinessmodel.com/blogs/brief-history/ceribell-brief-history ↩

  4. https://www.fogartyinnovation.org/an-afternoon-with-ceribells-jane-chao/ ↩ ↩2 ↩3

  5. https://www.prnewswire.com/news-releases/ceribell-inc-announces-pricing-of-upsized-initial-public-offering-302273634.html ↩ ↩2

  6. https://www.fastcompany.com/91226611/ceribell-ceo-jane-chao-seizure-detection-device-ai-future-eeg ↩ ↩2

  7. https://www.fiercebiotech.com/medtech/ceribell-rings-50m-seizure-spotting-portable-eeg-headset ↩ ↩2

  8. https://www.prnewswire.com/news-releases/ceribell-announces-completion-of-53-million-series-c-financing-301280436.html ↩ ↩2

  9. https://www.ajmc.com/view/ceribell-s-status-epilepticus-software-receives-fda-clearance-with-cms-ntap-coverage-included ↩

  10. https://www.globenewswire.com/fr/news-release/2025/04/15/3061653/0/en/FDA-Clears-Ceribell-s-Clarity-Algorithm-for-Pediatric-Patients-Making-Ceribell-the-First-and-Only-FDA-Cleared-AI-Technology-for-Detection-of-Electrographic-Seizures-in-Patients-Age.html ↩

  11. https://www.marketbeat.com/instant-alerts/ceribell-conference-cfo-highlights-36-revenue-growth-expands-eeg-platform-to-pediatrics-and-delirium-2026-03-07/ ↩ ↩2 ↩3 ↩4 ↩5 ↩6

  12. https://www.medtechdive.com/news/ceribell-clearance-seizure-detection-neonates/806376/ ↩

  13. https://news.google.com/rss/articles/CBMi8gFBVV95cUxOQVFBR3ZwS1IxcGRmMW1nU3hSdVhiS1dMcXBiTlJzSnB6UlZObFI4M1VERWp5c3k3czhORFZUVENsNGJJNjZmNmNIQkV5YkdUVjdmZG5LNzVSLTVnaDREc1lwaTEtLXhMSDA4WllmZFRjaDJuN0o3d3B2NUpTTEYxcjFiY211TWxFN2ZRbGdPVDYzSkhDZmp4a2JINTVVMW4tTjY2QmNseEIzOC0zV1l6M29YaG1yYlJJOGZXMk90ZnRUVmJOS09FQlEyRE1DNjZqU0VwRnBsaVFuYlJLbVZVeWZRRV9IUHJUUlJyT01jTWhwZw?oc=5 ↩ ↩2

  14. https://www.linkedin.com/posts/ceribell_breaking-news-last-week-ceribell-received-activity-7406356176503832576-Npkc ↩

  15. https://ceribell.gcs-web.com/news-releases/news-release-details/ceribell-receives-fda-breakthrough-device-designation-lvo-stroke ↩

  16. https://hitconsultant.net/2026/01/05/the-eeg-as-a-vital-sign-ceribells-ai-pivot-to-in-hospital-stroke-detection/ ↩

  17. https://www.nasdaq.com/press-release/ceribell-reports-fourth-quarter-and-full-year-2025-financial-results-2026-02-24 ↩

  18. https://news.google.com/rss/articles/CBMijwFBVV95cUxNQXRwUWhMaWRWeWNDWFBRZjcxSjI4U1ZVR1ljS1BTblVqUHotUVVsQjBMdkhlbDBSUm5GOWtkWlNtTExybFUxRTFYei1HalNCUk9xMTJzck1SX1VPNncwNmZKM1NjVk9WbE5wVk5FMWVEZlp5aTk5MURrdHVTM2dReGxRaGlBUS1jX25BeXIzWQ?oc=5 ↩

  19. https://news.google.com/rss/articles/CBMimwFBVV95cUxQdGhwcXpFckJaZkdyS3lzZV9PaGFFWmxkYk9HY0E4WHc1SHMyMXJrY3ItUnc4cGdzcjhjMTNMOEVoMnFtNE1oNGZmbU1HWkJMTlJrSWV5aW04UXJ4WGhmbjFHS0dnQy01bnBIWTN2Q0xfSDNlNTYzSWx6N2pIZVAzVmZYNXF2NVhXdFFaY29UekNudmxmd3BBZnh4OA?oc=5 ↩

  20. https://news.google.com/rss/articles/CBMisAFBVV95cUxOSzdPSW15UmsteVRoZHE3ZHRiYkpGeGk4RFlpdl84SlNESjVPNnRoQkc4WFBndnlrZFlLRUxjTVJ2dFdRbjFqTlZyX0RoeEJDZEV6NmZlZFBTWlFDaXlkdzFaWEJiYW83S25yQzlld2U0ams4LWo4ZkFyU0pkZkRrUzBadFF5TTh3SG83NUVGSU02ZzBYTjFwcWlYdndHVDhJVEVKNW5PV0pNOWxMc0lvcA?oc=5 ↩

  21. https://ceribell.com/evidence/clinical-studies/ ↩ ↩2

  22. https://ceribell.gcs-web.com/news-releases/news-release-details/ceribell-launches-clarityprotm-ai-expanding-access-critical ↩

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