- Brain tissue response to DBS electrodes and how that interaction affects therapy remain incompletely understood despite widespread use of DBS for neurological and neuropsychiatric conditions.1
- A review in Journal of Neural Engineering identified 33 cases with 63 electrodes from patients with various disease pathologies and DBS targets, and supplemented findings with animal studies.1
- Neurohistopathological and animal data can inform device design and chronic implantation and guide future neurohistopathological studies.1 1