Neural Noise

Less invasive brainwave recording for BCI

2 min read

  • A less invasive brainwave recording breakthrough was reported (EurekAlert!, September 2025), directly addressing neural recording and less-invasive interfaces key for BCI adoption.
  • The work is indicated as peer-reviewed and tier-1 for device and methods pipeline. 1

Gardner updates

  • A less invasive brainwave recording breakthrough was reported, with relevance to BCI adoption and device/methods pipelines. 1

Weekly enrichment (2026-07-20)

  • The breakthrough is a University of Osaka study led by Professor Takufumi Yanagisawa (lead author Dr. Takamitsu Iwata), published in Advanced Intelligent Systems (DOI 10.1002/aisy.202500487) and announced September 2025, demonstrating intravascular EEG (ivEEG) recorded from within brain blood vessels using ultra-thin microintravascular wire electrodes threaded by catheter.23
  • In eight pigs, recordings from small, soft cortical veins (CV-ivEEG) achieved higher resting-state signal power and greater spatial resolution of somatosensory evoked potentials (SEPs) than electrodes placed in the large superior sagittal sinus (SSS).3
  • ivEEG electrodes advanced into deep veins clearly captured visual evoked potentials, showing access to deep brain regions that are difficult to reach non-invasively.32
  • Head-to-head comparisons in two pigs showed CV-ivEEG captured cortical SEPs comparable to electrocorticography (ECoG) recorded with epidural and subdural electrodes, the current invasive reference standard.3
  • Targeted electrical stimulation delivered through cortical-vein electrodes evoked specific contralateral muscle contractions (including face and shoulder responses) in five anesthetized pigs, confirming selective motor-region stimulation with minimal invasiveness.32
  • Because the method avoids craniotomy and direct cortical penetration, it is positioned as a bridge between low-precision scalp EEG and higher-risk invasive recording for epilepsy diagnosis, functional mapping, and next-generation BCIs.24
  • Lead researcher Dr. Takamitsu Iwata framed the advance as unlocking study of deep brain function and potentially enabling communication and device control for people with severe paralysis; the report was dated September 22, 2025.45
  • The work extends the endovascular BCI paradigm pioneered by Synchron’s Stentrode, whose 16-channel array is deployed in the superior sagittal sinus adjacent to motor cortex; accessing smaller cortical veins targets the finer hand- and mouth-movement regions that large-vessel stents cannot reach.63

Footnotes

  1. https://news.google.com/rss/articles/CBMiXEFVX3lxTFBLaHBjMzNXZk4zREtXQk1VNk44NEg0cHk5UWk3d09Sa1pfYmlPcE1vSS0xZGsyR1UyeDY0amtRVThYb05CZElpTVcteF92SGFER1V5YUo4ZHVhdk92?oc=5 ↩ ↩2

  2. https://www.eurekalert.org/news-releases/1099188 ↩ ↩2 ↩3 ↩4

  3. https://doi.org/10.1002/aisy.202500487 ↩ ↩2 ↩3 ↩4 ↩5 ↩6

  4. https://medicalxpress.com/news/2025-09-invasive-brainwave-blood-vessels-access.html ↩ ↩2

  5. https://ir.library.osaka-u.ac.jp/repo/ouka/all/102962/ ↩

  6. https://www.medrxiv.org/content/10.1101/2025.09.19.25335897v1.full.pdf ↩

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