- Time-varying covariation of oscillatory amplitudes across two brain regions can be quantified from local field potentials (LFP) using extensions of Canonical Correlation Analysis (CCA) to multiple time series.1
- The approach targets high-dimensional multi-electrode recordings (e.g. 96 electrodes per region) during tasks such as memory.1
- Identifying coordinated oscillatory activity across regions in such high-dimensional LFP data remains a methodological challenge that this CCA-based framework addresses.1 1