Neural Noise- Organotypic human brain slice cultures (hBSCs) from resected cortical tissue of epilepsy surgery patients can serve as a translational screening platform for novel neuromodulation devices.1
- Viable hBSCs support GCaMP-based calcium imaging, multi-electrode array (MEA) recordings, and immunohistochemical readouts such as c-Fos.1
- Magnetoelectric nanoparticles (MENPs) have been demonstrated as a representative neurostimulation modality in this human-tissue platform.1 1